MD/PhD Program
Program Faculty
Clicking on the faculty member's name will take you thier Faculty Interests Profile page for more information regarding thier area of research.
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Emad S. Alnemri, PhD Molecular mechanisms of apoptosis; Role of inflammation in cancer |
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Andrew E. Aplin, PhD Mutant B-RAF and integrin signaling in melanoma |
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Jeffrey L. Benovic, PhD Dysregulation of G protein signaling in cancer |
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Bruno Calabretta, MD, PhD Mechanisms of leukemogenesis by oncogenic tyrosine kinases |
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Gino Cingolani, PhD Nucleocytoplasmic transport; Virus assembly; Multisubunit ATPases; Structural and biophysical techniques |
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Manuel L. Covarrubias, MD, PhD Function, structure and pharmacology of voltage-gated ion channels in excitable tissues |
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Laurence C. Eisenlohr, VMD, PhD Antigen processing and presentation; Anti-viral responses; Vaccine development; tolerance and autoimmunity; Cancer immunotherapy |
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Andrzej Fertala, PhD Heritable diseases of connective tissues. |
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Mark E. Fortini, PhD Notch receptor signaling in tissue formation; Biochemical and cell biological events regulating Notch activation |
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Linda Greenbaum, MD Transcriptional control of hepatocyte proliferation; Signaling pathways in hepatic progenitor cells regulating liver repair and carcinogenesis |
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Noreen J. Hickok, PhD Bone-bacterial-biomaterial interface; Mechanisms of bacterial colonization and biofilm formation; Therapies to interrupt bacterial adhesion and host tissue colonization |
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Jan B. Hoek, PhD Effects of ethanol on integrated signaling responses in liver; Cell signaling and mitochondrial function; Signaling associated with liver homeostasis, stress responses, and regeneration |
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D. Craig Hooper, PhD Neuroimmunology and viral infections |
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Lorraine Iacovitti, PhD Stem cells to study and treat Parkinson's disease; Neuroprotective agents to treat Parkinson's Disease; Stem cells to treat stroke; Sites of adult stem cells in brain |
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Renato V. Iozzo, MD Proteoglycan control of cancer growth and angiogenesis; Tumor microenvironment and regulation of receptor tyrosine kinases by matrix molecules |
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Karen E. Knudsen, PhD Hormone signaling in the male reproductive tract; Impact of androgen receptor function on prostate development and disease |
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My G. Mahoney, PhD Role of desmosomal proteins in cell adhesion, signaling, morphogenesis, and skin cancer development |
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Tim Manser, PhD Antigen-dependent stages of B cell differentiation leading to the generation of B cell memory |
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Alexander Mazo, PhD Epigenetic function of Drosophila ortholog of the MLL oncogene |
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James P. McGettigan, PhD Investigating vaccine-induced T and B cell responses against viral infections |
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Steven B. McMahon, PhD Deregulation of the p53 and MYC transcription networks driving cancer |
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A. Sue Menko, PhD Signaling mediating acquisition of the differentiated cell phenotype; Cell adhesion and the cytoskeleton in regulating tissue morphogenesis, regeneration, and fibrosis |
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Diane E. Merry, PhD Molecular determinants of androgen receptor metabolism and of polyglutamine-expanded androgen receptor misfolding and aggregation |
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Michael O'Leary, PhD Molecular mechanisms of sensory transduction in the peripheral nervous system |
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Michael Oshinsky, PhD Recurrent episodic headache syndromes |
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John M. Pascal, PhD Structural biology and biochemistry of the DNA damage response and mechanisms for maintaining genetic integrity |
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Fabienne M. Paumet, PhD Role of phagocytosis in the pathogenesis of infectious diseases; Role of phagocytosis in mast cell function in allergy |
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Richard G. Pestell, MD, PhD Cell cycle control in cancer. |
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Natalia A. Riobo, PhD Role and mechanisms of Hedgehog signaling in proliferation, survival and cell migration |
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Makarand V. Risbud, PhD Intervertebral disc biology; Hypoxic tissue niches; Stem cell biology; Tissue engineering and regenerative medicine |
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Michael J. Root, MD, PhD Mechanisms of viral and cell-cell membrane fusion; HIV entry inhibitor design and vaccine development; Osteoclast formation/macrophage fusion. |
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Abdolmohamad Rostami, MD, PhD Helper T cell subsets and their cytokines in the pathogenesis of autoimmune encephalomyelitis (EAE) and multiple sclerosis; Effect of the Bowman-Birk serine protease inhibitor on the course of EAE; Mechanisms of intravenous tolerance in EAE; Effects of interleukin-27 (IL-27) on human auto-aggressive T cells |
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Hallgeir Rui, M.D., PhD Molecular biology and signaling by receptors for lactogenic hormones; Endocrine regulation of breast cancer |
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Jay S. Schneider, PhD Parkinson's disease; Heavy metal neurotoxicity |
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Matthias J. Schnell, PhD Development of novel vaccines and viral pathogenesis |
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Irving M. Shapiro, PhD Chondrocyte apoptosis and autophagy; Stem cell function in the intervertebral disc; Development of methods to attach bioactive substances to metals utilized for orthopaedic implants |
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Linda D. Siracusa, PhD Genetics of cancer susceptibility |
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Yuri K. Sykulev, MD, PhD Molecular mechanisms regulating cytotoxic T lymphocyte activity |
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Theodore F. Taraschi, PhD Role of defective DNA mismatch repair in the development of antimalarial drug resistance |
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Davide Trotti, PhD Mechanisms of neurodegeneration in amyotrophic lateral sclerosis |
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Jouni Uitto, MD, PhD Biology of connective tissue related to cutaneous diseases that increase the risk of aggressive squamous cell carcinomas |
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Elisabeth J. Van Bockstaele, PhD Cannabinoid modulation of noradrenergic circuits; Stress and vulnerability to psychiatric disorders; Opioid receptor signaling and interacting proteins; Mechanisms of synaptic plasticity; Neurotransmitter release and receptor dynamics |
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Scott A. Waldman, MD, PhD Tumor suppressors and their signaling pathways in GI malignancies; Targeted diagnostics and therapeutics in cancer |
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Philip B. Wedegaertner, PhD Heterotrimeric G protein regulation of intracellular trafficking; Role of RhoGEFs in mitosis |
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Eric Wickstrom, PhD Genetic diagnosis of cancer by imaging activated mRNAs in tumors; Analysis of circulating tumor cells; Genetic therapy of cancer by knockdown of activated genes and miRNAs |
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Edward Winter, PhD Molecular/genetic analyses of signaling and transcriptional regulation using meiotic development in S. cerevisiae as a model |
