Research

Faculty members in the Acute Care Surgery Division head funded research projects, publish in peer-reviewed journals, author book chapters and present frequently at local and national conferences. Funded programs from recent years include the following:

Protocol LEX-205 Randomized Open-Label, Efficacy and Safety Study of Octaplex and Fresh Frozen Plasma (FFP) in Patients under Vitamin K Antagonist Therapy with the Need for Urgent Surgery or Invasive Procedures.

Octapharma, 2008
Principal Investigator: Michael Weinstein

Concentrated Prothrombin versus FFP in Emergency Surgery for Patients on Coumadin.

2007
Principal Investigator: Michael Weinstein
Co-Investigators: Kris Kaulback, Murray Cohen, Gary Lindenbaum, Pankaj Patel

Amgen Protocol Number 92004560 An Exploratory Study to Characterize the Variability in 11-betaHSD-1 Activity in Subcutaneous Adipose Tissue of Obese Diabetic Subjects and Healthy Controls.

Amgen 2004  $10,000 surgical grant
Principal Investigator: Walter Kraft
Co-Investigator: Kris Kaulback

CAPSS-151 A Multicenter, Open-Label, Randomized Study of Once Daily Levofloxacin Along with Once Daily Metronidazole versus Piperacillin/Tazobactam in the Treatment of Complicated Appendicitis

Ortho-McNeil, 2004 
Principal Investigator: Pauline Park
Co-Investigators: Kris Kaulback, Michael Weinstein

Procrit  A Prospective Multicenter Study of the Anemia of Critical Illness and Transfusion in the Critically Ill Patient.

2000
Principal Investigator: Murray Cohen
Co-Investigators: Kris Kaulback, Michael Weinstein

Prospective, Randomized, Multi-Center Trial of Pulmonary Artery Catheter vs Central Venous Catheter and ‘Fluid Conservative vs ‘Fluid liberal’ Management of Acute Lung Injury and ARDS

Principal Investigator: Jonathon Gottlieb
Co-Investigator: Michael Weinstein

The Acute Respiratory Distress Syndrome Network, Prospective, Randomized, Multi-Center Trial of Higher PEEP/Lower FiO2 versus Lower PEEP/Higher FiO2 Ventilation in Acute Lung Injury and Acute Respiratory Distress Syndrome.

NIH/NHLBI ARDS Clinical Network Contracts NO1-HR 46054-64, 1999
Principal Investigator: Jonathan Gottlieb
Co-Investigators: Kris Kaulback, Michael Weinstein