Division of Molecular Radiation Biology
Stem Cells
This research is based on a new paradigm emerging in oncology; the only truly effective way to prevent or treat cancer is to selectively target cancer stem cells (CSC). This view is supported by mounting evidence that overpopulation of CSC drives tumor initiation & progression and that CSCs are relatively resistant to conventional therapies. Our goal is to identify mechanisms that regulate normal stem cell (SC) population size in tissues, and to determine how dysregulation of these mechanisms leads to stem cell overpopulation and cancer development. Understanding these mechanisms would provide a rationale for development of therapeutics that target and eliminate CSC.
Faculty
- Adam Dicker, MD, PhD
Professor, Chairman and Director, Experimental Radiation Oncology Division - Bo Lu, MD, PhD
Professor, Director, Division of Molecular Radiation Biology - Dennis B. Leeper, PhD
Professor and Founding Director - Ullrich Rodeck, MD
Professor of Dermatology - Phyllis R. Wachsberger, PhD
Assistant Professor - Richard Lawrence, MD
Assistant Professor
Adjunct Faculty
- George Iliakis, PhD
Professor, University of Essen, DL - Andrew J. Milligan, Jr, PhD
Professor, President of Bionix Medical Technologies - Ya Wang, MD, PhD
Professor, Emory University - Randy Burd, PhD
Assistant Professor, University of Arizona
