1020 Locust Street
Jefferson Alumni Hall,
Suite 336C
Philadelphia, PA 19107
(215) 503-5066
Jefferson Alumni Hall,
Suite 336C
Philadelphia, PA 19107
(215) 503-5066
Most Recent Peer-reviewed Publications
- MicroRNA profiling in lung cancer reveals new molecular markers for diagnosis
- Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists
- The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma
- Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists
- Activation of Rho and Rho-associated kinase by GPR54 and KiSS1 metastasis suppressor gene product induces changes of cell morphology and contributes to apoptosis
- KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis
- Physical association of GPR54 C-terminal with protein phosphatase 2A
- Association of nucleophosmin negatively regulates CXCR4-mediated G protein activation and chemotaxis
- Heat shock response in C 1270 HO mammalian cells is controlled by a nonlinear stochastic process
- SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54
- Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy
- Structure-activity relationship study on small peptidic GPR54 agonists
- Characterization of constitutively active mutants of G protein-coupled receptors.
- Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity
- Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: A potential mechanism for the metastasis suppressor activity of kisspeptins
- Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2
- S-protein is expressed in necrotic fibers in Duchenne muscular dystrophy and polymyositis
- CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion
- Role of CD4 hinge region in GP120 utilization by immunoglobulin domain 1
- A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists