05B4 Iacovitti, Lorraine - Jefferson Medical College - Thomas Jefferson University
Lorraine Iacovitti, PhD

Lorraine Iacovitti, PhD

Contact Dr.  Iacovitti

900 Walnut Street
Philadelphia, PA 19107

(215) 955-8118
(215) 955-2992 fax

Most Recent Peer-reviewed Publications

  1. Gremlin is a novel VTA derived neuroprotective factor for dopamine neurons
  2. Changes in host blood factors and brain glia accompanying the functional recovery after systemic administration of bone marrow stem cells in ischemic stroke rats
  3. Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (ΔE) TorsinA in transgenic mice
  4. VTA neurons show a potentially protective transcriptional response to MPTP
  5. Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats
  6. Heterotopically transplanted CVO neural stem cells generate neurons and migrate with SVZ cells in the adult mouse brain
  7. Genetic ablation of caveolin-1 increases neural stem cell proliferation in the subventricular zone (SVZ) of the adult mouse brain
  8. Functional heterogeneity at dopamine release sites
  9. Human amniotic fluid stem cells do not differentiate into dopamine neurons in vitro or after transplantation in vivo
  10. Circumventricular organs: A novel site of neural stem cells in the adult brain
  11. The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model
  12. Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra
  13. Transcription and epigenetic profile of the promoter, first exon and first intron of the human tyrosine hydroxylase gene
  14. A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo
  15. Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease
  16. Tyrosine hydroxylase gene regulation in human neuronal progenitor cells does not depend on Nurr1 as in the murine and rat systems
  17. Purified mouse dopamine neurons thrive and function after transplantation into brain but require novel glial factors for survival in culture.
  18. Purified mouse dopamine neurons thrive and function after transplantation into brain but require novel glial factors for survival in culture
  19. Characterization of five evolutionary conserved regions of the human tyrosine hydroxylase (TH) promoter: Implications for the engineering of a human TH minimal promoter assembled in a self-inactivating lentiviral vector system
  20. Studies on the differentiation of dopaminergic traits in human neural progenitor cells in vitro and in vivo
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