2238 Holinstat, Michael - Jefferson Medical College - Thomas Jefferson University
mah010

Michael Holinstat, PhD

Contact Dr. Holinstat

1015 Walnut Street
Suite 320
Philadelphia, PA 19107

(215) 955-6121
(215) 955-9170 fax

Most Recent Peer-reviewed Publications

  1. Investigations of human platelet-type 12-lipoxygenase: Role of lipoxygenase products in platelet activation
  2. Dichotomous effects of exposure to bivalirudin in patients undergoing percutaneous coronary intervention on protease-activated receptor-mediated platelet activation
  3. Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation
  4. Rap1-Rac1 circuits potentiate platelet activation
  5. We can do it together: PAR1/PAR2 heterodimer signaling in VSMCs
  6. Protein kinase Cα phosphorylates the TRPC1 channel and regulates store-operated Ca 2+ entry in endothelial cells (Journal of Biological Chemistry (2004) 279, (20941-20949))
  7. Discovery of potent and selective inhibitors of human platelet-type 12-lipoxygenase
  8. 12-lipoxygenase: A Potential Target for Novel Anti-Platelet Therapeutics
  9. Protease-activated receptor signaling in platelets activates cytosolic phospholipase a 2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis
  10. Role of protein kinase Cζ in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers
  11. Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates
  12. Erratum: Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway (Molecular Pharmacology (2007) 71 (686-694))
  13. PAR1, but not PAR4, activates human platelets through a G i/o/phosphoinositide-3 kinase signaling axis
  14. Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway
  15. PAR4, but not PAR1, signals human platelet aggregation via Ca 2+ mobilization and synergistic P2Y 12 receptor activation
  16. G-protein-coupled receptors: Evolving views on physiological signalling: Symposium on G-P 07AD rotein-Coupled Receptors: Evolving Concepts and New Techniques
  17. Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: Role in regulation of endothelial permeability
  18. Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1
  19. Interaural level difference processing in the lateral superior olive and the inferior colliculus
  20. Protein kinase Cα phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells
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