1025 Walnut Street
College Building, Room 901
Philadelphia, PA 19107
(215) 955-5614
(215) 955-5553 fax
College Building, Room 901
Philadelphia, PA 19107
(215) 955-5614
(215) 955-5553 fax
Most Recent Peer-reviewed Publications
- Biosynthetic pathways and the role of the mas receptor in the effects of angiotensin-(1-7) in smooth muscles
- Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function
- Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS
- RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincter
- Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells
- Role of rho kinase in the functional and dysfunctional tonic smooth muscles
- Basal internal anal sphincter tone, inhibitory neurotransmission, and other factors contributing to the maintenance of high pressures in the anal canal
- 3-Hydroxymethyl coenzyme A reductase inhibition attenuates spontaneous smooth muscle tone via RhoA/ROCK pathway regulated by RhoA prenylation
- RhoA/Rho-Kinase: Pathophysiologic and Therapeutic Implications in Gastrointestinal Smooth Muscle Tone and Relaxation
- Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells
- Arachidonic acid metabolites follow the preferential course of cyclooxygenase pathway for the basal tone in the internal anal sphincter
- Role of RHO Kinase in Gastrointestinal Motility
- COX-1 vs. COX-2 as a determinant of basal tone in the internal anal sphincter
- Sympathetic (Adrenergic) Innervation Modulates But Does Not Generate Basal Tone in the Internal Anal Sphincter Smooth Muscle
- Selectivity of ROCK inhibitors in the spontaneously tonic smooth muscle
- PET imaging of VPAC1 expression in experimental and spontaneous prostate cancer
- Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) receptor specific peptide analogues for PET imaging of breast cancer: In vitro/in vivo evaluation
- Role of phospholipase A2 (group I secreted) in the genesis of basal tone in the internal anal sphincter smooth muscle
- Cellular regulation of basal tone in internal anal sphincter smooth muscle by RhoA/ROCK
- RhoA prenylation inhibitor produces relaxation of tonic smooth muscle of internal anal sphincter