833 Chestnut Street
Suite 301
Philadelphia, PA 19107
(215) 955-7190
(215) 955-8600 fax
Suite 301
Philadelphia, PA 19107
(215) 955-7190
(215) 955-8600 fax
Most Recent Peer-reviewed Publications
- Intracellular sodium determines frequency-dependent alterations in contractility in hypertrophied feline ventricular myocytes
- Phosphorylation of phospholamban at threonine-17 reduces cardiac adrenergic contractile responsiveness in chronic pressure overload-induced hypertrophy
- Ca 2+ influx-induced sarcoplasmic reticulum Ca 2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes
- Alterations in early action potential repolarization causes localized failure of sarcoplasmic reticulum Ca 2+ release
- Pharmacological effects of ATI22-107 [2-(2-{2-[2-chloro-4-(6-oxo-1,4,5,6- tetrahydro-pyridazin-3-yl)-phenoxy]-acetylamino}-ethoxymethyl) -4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester)], a novel dual pharmacophore, on myocyte calcium cycling and contractility