233 South Tenth Street
Bluemle Life Sciences Building, Suite 409
Philadelphia, PA 19107
(215) 503-5622
(215) 503-5788 fax
Bluemle Life Sciences Building, Suite 409
Philadelphia, PA 19107
(215) 503-5622
(215) 503-5788 fax
Most Recent Peer-reviewed Publications
- Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma
- Integration of investigative dermatology into the global biomedical research enterprise: Past, present, and future
- Autoregulation of kinase dephosphorylation by ATP binding to AGC protein kinases
- A novel preclinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicity
- Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity
- PET imaging of EGFR expression in nude mice bearing MDA-MB-468, a human breast adenocarcinoma
- Differential regulation of p53 function by the N-terminal Np53 and 113p53 isoforms in zebrafish embryos
- A novel class of compounds with cutaneous wound healing properties
- Progress in epidermolysis bullosa research: Toward treatment and cure
- Design and development of masked therapeutic antibodies to limit off-target effects: Application to anti-EGFR antibodies
- Nuclear factor κB inhibitors alleviate and the proteasome inhibitor PS-341 exacerbates radiation toxicity in zebrafish embryos
- Tumor necrosis factor-α and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice
- Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development
- Skin toxicity caused by EGFR antagonists-an autoinflammatory condition triggered by deregulated IL-1 signaling?
- Nature's design: A blueprint for engineered therapeutic antibodies
- Biochemical and structural characterization of the Pak1-LC8 interaction
- Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity
- Cells expressing partially unfolded R789C/p.R989c type II procollagen mutant associated with spondyloepiphyseal dysplasia undergo apoptosis
- Inhibition of p73 function by Pifithrin-α as revealed by studies in zebrafish embryos
- Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425