05B4 Languino, Lucia - Jefferson Medical College - Thomas Jefferson University
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Lucia Languino, PhD

Contact Dr. Languino

233 South 10th Street
Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β 1 integrin-RACK1 axis
  2. Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s
  3. PSA regulates androgen receptor expression in prostate cancer cells
  4. α vβ 6 integrin expression is induced in the POET and Pten pc-/- mouse models of prostatic inflammation and prostatic adenocarcinoma
  5. TRAP-1, the mitochondrial Hsp90
  6. Insulin-like growth factor 1 stimulation of androgen receptor activity requires β 1A integrins
  7. The search for a better prostate cancer biomarker
  8. Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease
  9. Preclinical characterization of mitochondria-targeted small molecule Hsp90 inhibitors, gamitrinibs, in advanced prostate cancer
  10. β1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1
  11. CD133, Trop-2 and α2β1 integrin surface receptors as markers of putative human prostate cancer stem cells
  12. The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFβ in prostate cancer cells
  13. Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer
  14. Runx2 association with progression of prostate cancer in patients: Mechanisms mediating bone osteolysis and osteoblastic metastatic lesions
  15. IAP Regulation of Metastasis
  16. Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer
  17. Integrin signaling aberrations in prostate cancer
  18. Editorial: The launch of the American Journal of Translational Research
  19. Prostate cancer regulatory networks
  20. β1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1