2238 Chellappagounder, Thangavel - Jefferson Medical College - Thomas Jefferson University
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Thangavel Chellappagounder, PhD

Contact Dr. Chellappagounder

233 South 10th Street
Suite 1002
Philadelphia, PA 19107

(215) 503-8576

Most Recent Peer-reviewed Publications

  1. Inherent sex-dependent regulation of human hepatic CYP3A5
  2. Regulation of miR106b cluster through the RB pathway: Mechanismand functional targets
  3. Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men
  4. RB Restricts DNA Damage-Initiated Tumorigenesis through an LXCXE-Dependent Mechanism of Transcriptional Control
  5. Therapeutically activating RB: Reestablishing cell cycle control in endocrine therapy-resistant breast cancer
  6. The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
  7. Therapeutic CDK4/6 inhibition in breast cancer: Key mechanisms of response and failure
  8. Proliferative Suppression by CDK4/6 Inhibition: Complex Function of the Retinoblastoma Pathway in Liver Tissue and Hepatoma Cells
  9. Regulation of RB transcription in vivo by RB family members
  10. Retinoblastoma/p107/p130 pocket proteins. Proteins dynamics and interactions with target gene promoters
  11. Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats
  12. Prolactin stimulates ubiquitination, initial internalization, and degradation of its receptor via catalytic activation of Janus kinase 2
  13. Sex-dependent expression of CYP2C11 in spleen, thymus and bone marrow regulated by growth hormone
  14. Attenuated expression of episodic growth hormone-induced CYP2C11 in female rats associated with suboptimal activation of the Jak2/Stat5B and other modulating signaling pathways
  15. Determinants of growth hormone receptor down-regulation
  16. A molecular basis for the sexually dimorphic response to growth hormone
  17. Inducibility of male-specific isoforms of cytochrome P450 by sex-dependent growth hormone profiles in hepatocyte cultures from male but not female rats
  18. Sexually dimorphic regulation of hepatic isoforms of human cytochrome P450 by growth hormone
  19. Intrinsic sex differences determine expression of growth hormone-regulated female cytochrome P450s
  20. Epidermal growth factor regulation of female-dependent CYP2A1 and CYP2C12 in primary rat hepatocyte culture
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