05B4 Casimiro, Mathew - Jefferson Medical College - Thomas Jefferson University
mcc111

Mathew C. Casimiro, PhD

Contact Dr. Casimiro

233 South 10th Street
Suite 1035
Philadelphia, PA 19107

(215) 503-9350
(215) 923-4498 fax

Most Recent Peer-reviewed Publications

  1. Novel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures
  2. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth
  3. Cyclin D1 induces chromosomal instability
  4. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice
  5. Mammary gland selective excision of c-Jun identifies its role in mRNA splicing
  6. Caveolin-1 overexpression enhances androgen-dependent growth and proliferation in the mouse prostate
  7. Examining the role of cyclin D1 in breast cancer
  8. Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation
  9. Cell fate determination factor Dachshund reprograms breast cancer stem cell function
  10. The canonical NF-κB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion
  11. C-jun inhibits mammary apoptosis in vivo
  12. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism
  13. HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis
  14. Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": A transcriptional informatics analysis with validation
  15. Attenuation of Forkhead signaling by the retinal determination factor DACH1
  16. Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: Similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"
  17. Activating peroxisome proliferator-activated receptor γ mutant promotes tumor growth in vivo by enhancing angiogenesis
  18. The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
  19. p21 CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo
  20. PPARγ activation induces autophagy in breast cancer cells
0