233 South 10th St
Suite 630 A
Philadelphia, PA 19107
(215) 503-4522
Suite 630 A
Philadelphia, PA 19107
(215) 503-4522
Most Recent Peer-reviewed Publications
- Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion
- Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
- The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: Correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform
- Expression of p89 c-Mybex9b, an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells
- Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells
- c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
- Suppression of autophagy by BCR/ABL
- TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER + breast cancer cells
- Regulation of microRNA-145 by growth arrest and differentiation
- Inhibition of autophagy: A new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors
- Expression of the transcriptional repressor Gfi-1 is regulated by C/EBPα and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells
- The biological effects of C/EBPα in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain
- Expression of slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin
- Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model
- Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
- Transcriptional re 07E5 pression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPα in p210 BCR/ABL-expressing cells
- Slug (SNAI2) down-regulation by interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models
- Requirement of c-Myb for p210 BCR/ABL-dependent transformation of hematopoietic progenitors and leukemogenesis
- Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk
- Activation of p53-dependent responses in tumor cells treated with a PARC-interacting peptide