05B4 Mazo, Alexander M. - Jefferson Medical College - Thomas Jefferson University
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Alexander M. Mazo, PhD

Contact Dr. Mazo

1020 Locust Street
JAH, Rm. 485
Philadelphia, PA 19107

(215) 503-4785
(215) 923-7144 fax

Most Recent Peer-reviewed Publications

  1. TrxG and PcG proteins but not methylated histones remain associated with DNA through replication
  2. Ecdysone- and NO-Mediated Gene Regulation by Competing EcR/Usp and E75A Nuclear Receptors during Drosophila Development
  3. Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation
  4. Regulatory noncoding RNAs at Hox loci
  5. Association of trxG and PcG proteins with the bxd maintenance element depends on transcriptional activity
  6. Transcriptional interferen An unexpected layer of complexity in gene regulation
  7. Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth
  8. A model for initiation of mosaic HOX gene expression patterns by non-coding RNAs in early embryos
  9. Transcription of bxd Noncoding RNAs Promoted by Trithorax Represses Ubx in cis by Transcriptional Interference
  10. A motif within SET-domain proteins binds single-stranded nucleic acids and transcribed and supercoiled DNAs and can interfere with assembly of nucleosomes
  11. ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia
  12. Purification and Biochemical Properties of the Drosophila TAC1 Complex
  13. Modulation of heat shock gene expression by the TAC1 chromatin-modifying complex
  14. Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila
  15. Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements
  16. ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation
  17. Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene
  18. huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions
  19. Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteins
  20. Trithorax and ASH1 interact directly and associate with the trithorax group-responsive bxd region of the Ultrabithorax promoter
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