233 South 10th Street
BLSB 231
Philadelphia, PA 19107
(215) 503-4616
(215) 503-5393 fax
BLSB 231
Philadelphia, PA 19107
(215) 503-4616
(215) 503-5393 fax
Most Recent Peer-reviewed Publications
- A role for SUMO in nucleotide excision repair
- Deficient SUMO attachment to flp recombinase leads to homologous recombination-dependent hyperamplification of the yeast 2 μm circle plasmid
- Ubc9 Sumoylation Regulates SUMO Target Discrimination
- Ubiquitin-dependent proteolytic control of SUMO conjugates
- Topoisomerase I-dependent viability loss in Saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair
- Small ubiquitin-related modifier pathway is a major determinant of doxorubicin cytotoxicity in Saccharomyces cerevisiae
- Multiple domains in Siz SUMO ligases contribute to substrate selectivity
- Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications
- Improved identification of SUMO attachment sites using C-terminal SUMO mutants and tailored protease digestion strategies
- Sumoylation of the yeast Gcn5 protein
- Defects in SUMO (small ubiquitin-related modifier) conjugation and deconjugation alter cell sensitivity to DNA topoisomerase I-induced DNA damage
- Misregulation of 2μm circle copy number in a SUMO pathway mutant
- Varshavsky's contributions [3]
- Global analysis of protein sumoylation in Saccharomyces cerevisiae
- Protein modification by SUMO
- The SUMO Isopeptidase Ulp2 Prevents Accumulation of SUMO Chains in Yeast
- Ubiquitin branches out
- An E3-like factor that promotes SUMO conjugation to the yeast septins
- SUMO conjugation and deconjugation
- Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins