233 South 10th St.
BLSB 830
Philadelphia, PA 19107
(215) 503-7322
BLSB 830
Philadelphia, PA 19107
(215) 503-7322
Most Recent Peer-reviewed Publications
- Introduction-Notch in development and disease
- Therapeutic approaches to modulating Notch signaling: Current challenges and future prospects
- Deficient Notch signaling associated with neurogenic pecanex is compensated for by the unfolded protein response in Drosophila
- Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function
- In Vivo reconstitution of γ-secretase in Drosophila results in substrate specificity
- Erratum to Retraction Notice to: The Big Brain Aquaporin Is Required for Endosome Maturation and Notch Receptor Trafficking [Cell, 133, (2008), 852-863]
- Pharmacological analysis of Drosophila melanogaster γ-secretase with respect to differential proteolysis of notch and APP
- Endocytic regulation of Notch signaling
- Generation and characterization of monoclonal antibodies specific to Drosophila presenilin
- Notch Signaling: The Core Pathway and Its Posttranslational Regulation
- The Big Brain Aquaporin Is Required for Endosome Maturation and Notch Receptor Trafficking
- Endosomal entry regulates Notch receptor activation in Drosophila melanogaster
- A role for presenilin in post-stress regulation: Effects of presenilin mutations on Ca 2+ currents in Drosophila
- Anticipating trouble from gene transcription
- Drosophila as a model for human diseases: IRB and ICREA, Barcelona, Spain, October 5-7, 2006.
- Modeling Clinically Heterogeneous Presenilin Mutations with Transgenic Drosophila
- γ-Cleavage-Independent Functions of Presenilin, Nicastrin, and Aph-1 Regulate Cell-Junction Organization and Prevent Tau Toxicity In Vivo 0542
- Notch signaling: A different sort makes the cut
- Functional reconstitution of γ-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2
- PAR-1 for the course of neurodegeneration