233, S. 10th Street
BLSB 904
Philadelphia, PA 19107
(215) 503-4632
(215) 923-1098 fax
BLSB 904
Philadelphia, PA 19107
(215) 503-4632
(215) 923-1098 fax
Most Recent Peer-reviewed Publications
- Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
- Translation termination factor eRF3 is targeted for caspase-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis
- Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
- Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012
- Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection
Medical School
PhD Temple University School of Medicine - 1991
Keywords
Apoptosis; Cell death; CPP32; Caspases; Pyrin; Nalp3; Inflammation; Innate immunity; Caspase-1; Pyroptosis; Pyroptosome; ASC; AIM; neurodegeneration; omi;